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Monitoring and follow-up should be arranged at 3 months initially to assess HbA1c response, tolerability, weight change, blood pressure, and renal function

Summary of preclinical research observations

Hence, further comprehensive investigations are required to elucidate the precise function of ferroptosis in the pathogenesis of IBD and other associated intestinal disorders

While many of these medications were initially approved for type 2 diabetes, several (e.g., semaglutide at higher doses, tirzepatide) have approvals or strong evidence for obesity management in nondiabetic populations